C₂₉H₃₄BN₃O₆

Base Information

• Chemical Name: C₂₉H₃₄BN₃O₆
• CAS No.: 1613056-67-9
• Molecular Formula: C₂₉H₃₄BN₃O₆
• Molecular Weight: 531.416
• Mol file: 1613056-67-9.mol

Synonyms:C₂₉H₃₄BN₃O₆

Chemical Property of C₂₉H₃₄BN₃O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₄BN₃O₆

There total 5 articles about C₂₉H₃₄BN₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C23H22BrN3O4 (1613056-66-8) + bis(pinacol)diborane (73183-34-3) → C29H34BN3O6 (1613056-67-9)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In N,N-dimethyl-formamide; at 90 ℃; for 3h; Inert atmosphere; Sealed tube;

Reference yield:

N-Benzyloxycarbonyl-L-proline (1148-11-4) → C29H34BN3O6 (1613056-67-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: magnesium chloride / tetrahydrofuran / 30 - 70 °C / Inert atmosphere; Sealed tube

1.2: 30 °C / Inert atmosphere; Sealed tube

2.1: acetic acid / toluene / 6 h / Inert atmosphere; Sealed tube; Reflux

2.2: 1.5 h / 235 °C / Inert atmosphere; Sealed tube

3.1: palladium on activated charcoal; hydrogen / methanol / 5 h / 40 °C / 7600.51 Torr / Inert atmosphere; Sealed tube

4.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere; Sealed tube

5.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate / N,N-dimethyl-formamide / 3 h / 90 °C / Inert atmosphere; Sealed tube

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium on activated charcoal; hydrogen; potassium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; magnesium chloride; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;

Reference yield:

(S)-benzyl 2-(3-ethoxy-3-oxopropanoyl)pyrrolidine-1-carboxylate (1357258-78-6) → C29H34BN3O6 (1613056-67-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid / toluene / 6 h / Inert atmosphere; Sealed tube; Reflux

1.2: 1.5 h / 235 °C / Inert atmosphere; Sealed tube

2.1: palladium on activated charcoal; hydrogen / methanol / 5 h / 40 °C / 7600.51 Torr / Inert atmosphere; Sealed tube

3.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere; Sealed tube

4.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate / N,N-dimethyl-formamide / 3 h / 90 °C / Inert atmosphere; Sealed tube

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium on activated charcoal; hydrogen; potassium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; N,N-dimethyl-formamide; toluene;

upstream raw materials:

C₂₃H₂₂BrN₃O₄

bis(pinacol)diborane

N-Benzyloxycarbonyl-L-proline

(S)-benzyl 2-(3-ethoxy-3-oxopropanoyl)pyrrolidine-1-carboxylate

Downstream raw materials:

C₅₈H₅₇N₇O₇