N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Base Information

Chemical Name:N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide
CAS No.:1422129-84-7
Molecular Formula:C₁₄H₁₇N₃O₂S
Molecular Weight:291.374
Hs Code.:

N,N-dimethyl-N<SUP>2</SUP>-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Synonyms:N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Suppliers and Price of N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Chemical Property:

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Technology Process of N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

There total 2 articles about N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123665-42-9,1175090-79-5
(S)-2-Amino-N,N-dimethyl-3-phenyl-propionamide hydrochloride

: 4303-29-1
4-thioxo-2-thiazolidinone

: 1422129-84-7
N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Guidance literature:: With triethylamine; In ethanol; for 20h;

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 1422129-84-7
N,N-dimethyl-N²-(2-oxo-2,5-dihydro-1,3-thiazol-4-yl)-L-phenylalaninamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide; water / 3 h / 20 °C

1.2: 20 °C / Cooling with ice

2.1: triethylamine / ethanol / 20 h

With triethylamine; N-ethyl-N,N-diisopropylamine; HATU; In ethanol; water; N,N-dimethyl-formamide;