Technology Process of 3-(triphenylstannyl)-all-trans-1,5,9-cyclododecatriene
There total 1 articles about 3-(triphenylstannyl)-all-trans-1,5,9-cyclododecatriene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; magnesium;
In
tetrahydrofuran;
byproducts: bi-all-trans-2,6,10-cyclododecatrien-1-yl; addn. of two drops of ttt-3-Br-CDT to Mg cuttings in THF under N2; boiling til start of the react.; dropwise addn. of ttt-3-Br-CDT and ClSnPh3 in THF; refluxing for 7 h; stirring at room temp. for 15 h; hydrolysis with a satd. aq. NH4Cl4 soln.;; extn. (ether); washing (water); drying; evapg. solvent; column chromy. (SiO2, benzine), collection (2nd fraction); dissolution (ether); shaking(methanol/ether (1:1)); sepn. of phases; washing (water); drying; evapg.solvent (vac.); cryst.; elem. anal.;
- Guidance literature:
-
With
phenyllithium;
In
diethyl ether; benzene;
for 1h;
Ambient temperature;
- Guidance literature:
-
With
1-bromo-butane; water;
In
diethyl ether;
byproducts: all-trans-1,5,9-cyclododecatriene; N2 atmosphere; addn. of PhLi to the triphenylstannyl compd. in ether atroom temp.; stirring at room temp. for 1 h; addn. of 1-bromobutane; stirring for 2 h; hydrolysis with water;; extg. (ether); washing (water); drying; evapn. of solvent; dissolution in acetone; filtration of Sn(C6H5)4;;
