(Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide

Base Information

• Chemical Name: (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide
• CAS No.: 1315563-24-6
• Molecular Formula: C₁₁H₁₂O₃S
• Molecular Weight: 224.28
• Mol file: 1315563-24-6.mol

Synonyms:(Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide

Chemical Property of (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide

There total 2 articles about (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H9BrO2S → (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide (1315563-24-6) + (E)-2-carbomethoxyethenyl o-methylphenyl sulfoxide (1315563-39-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 ℃;

DOI:10.1021/ol201508e

Reference yield:

o-bromothiophenol (6320-02-1) → (Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide (1315563-24-6) + (E)-2-carbomethoxyethenyl o-methylphenyl sulfoxide (1315563-39-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / -78 °C

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1021/ol201508e

Reference yield:

(Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide (1315563-24-6) + (2S)-2-[N-(tert-butoxycarbonyl)amino]-1-iodo-3-phenylpropane (154669-56-4) → C21H27NO3S + C21H27NO3S (1315563-35-9)

Guidance literature:

(Z)-2-carbomethoxyethenyl o-methylphenyl sulfoxide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

(2S)-2-[N-(tert-butoxycarbonyl)amino]-1-iodo-3-phenylpropane; In tetrahydrofuran; hexane; at -78 - 20 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol201508e

upstream raw materials:

o-bromothiophenol

Downstream raw materials:

C₂₁H₂₇NO₃S