(αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol

Base Information

• Chemical Name: (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol
• CAS No.: 102574-27-6
• Molecular Formula: C₁₆H₂₀O₃S₂
• Molecular Weight: 324.465
• Mol file: 102574-27-6.mol

Synonyms:(αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol

Chemical Property of (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol

There total 1 articles about (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

ethyl 2,3-C-(2-butene-1,4-diyl)-2,3-dideoxy-α-D-talo-pyranoside (86646-59-5) + Benzene-1,2-dithiol (17534-15-5) → (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol (102574-27-6)

Guidance literature:

With titanium tetrachloride; In dichloromethane; for 0.75h;

DOI:10.1021/jo00364a018

Reference yield: 65.0%

(αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol (102574-27-6) → (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde (102574-28-7)

Guidance literature:

With lead(IV) acetate; In benzene; for 0.5h;

DOI:10.1021/jo00364a018

Reference yield:

acetic anhydride (108-24-7) + (αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol (102574-27-6) → Acetic acid (1R,2R)-2,3-diacetoxy-1-((1R,6S)-6-benzo[1,3]dithiol-2-yl-cyclohex-3-enyl)-propyl ester

Guidance literature:

With pyridine; dmap; for 12h; Ambient temperature;

DOI:10.1021/jo00364a018

upstream raw materials:

ethyl 2,3-C-(2-butene-1,4-diyl)-2,3-dideoxy-α-D-talo-pyranoside

Benzene-1,2-dithiol

Downstream raw materials:

(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde