(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde

Base Information

• Chemical Name: (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde
• CAS No.: 102574-28-7
• Molecular Formula: C₁₄H₁₄OS₂
• Molecular Weight: 262.397
• Mol file: 102574-28-7.mol

Synonyms:(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde

Chemical Property of (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde

There total 1 articles about (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol (102574-27-6) → (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde (102574-28-7)

Guidance literature:

With lead(IV) acetate; In benzene; for 0.5h;

DOI:10.1021/jo00364a018

Reference yield: 96.0%

(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde (102574-28-7) → (1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenemethanol (102574-29-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h;

DOI:10.1021/jo00364a018

Reference yield:

(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenecarbaldehyde (102574-28-7) → (1R,6S)-6-Methyl-3-cyclohexene-1-carboxylic Acid (102629-35-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / LiAlH₄ / tetrahydrofuran / 1 h

2: 81 percent / NH₃, Na / tetrahydrofuran

3: 60 percent / Jones reagent / acetone / 0.5 h

With lithium aluminium tetrahydride; jones reagent; ammonia; sodium; In tetrahydrofuran; acetone;

DOI:10.1021/jo00364a018

upstream raw materials:

(αR,βR,1R,6S)-α,β-dihydroxy-6-(1,3-benzodithiol-2-yl)-3-cyclohexenepropanol

Downstream raw materials:

(1R,6S)-6-(1,3-benzodithiol-2-yl)-3-cyclohexenemethanol

(1R,6S)-6-Methyl-3-cyclohexene-1-carboxylic Acid

(1R,6S)-6-methyl-3-cyclohexenemethanol