Technology Process of 2-(4-(benzyloxy)phenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one
There total 11 articles about 2-(4-(benzyloxy)phenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 25 ℃;
for 6h;
Inert atmosphere;
DOI:10.1016/j.ejmech.2015.10.039
- Guidance literature:
-
2-(4-benzyloxy-phenyl)-5,6,7-trimethoxy-chromen-4-one;
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 1.5h;
Inert atmosphere;
With
methanol;
In
dichloromethane;
at 20 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2011.11.034
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium acetate / 1 h / 110 °C
2.1: boron trifluoride diethyl etherate; acetic acid / 5 h / 80 °C
3.1: pyridine / 15 h / 20 °C / Inert atmosphere
4.1: pyridine; potassium hydroxide / 3 h / 70 °C
4.2: Cooling with ice
5.1: sulfuric acid; acetic acid / 1.5 h / 80 °C
6.1: boron tribromide / dichloromethane / 1.5 h / 0 °C / Inert atmosphere
6.2: 0.5 h / 20 °C / Inert atmosphere
With
pyridine; sulfuric acid; boron trifluoride diethyl etherate; sodium acetate; boron tribromide; acetic acid; potassium hydroxide;
In
dichloromethane;
2.1: Fries rearrangement / 4.1: Baker-Venkataraman transformation;
DOI:10.1016/j.tetlet.2011.11.034