N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide

Base Information

Chemical Name:N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide
CAS No.:343-70-4
Molecular Formula:C₁₄H₁₂FN₃O₂S
Molecular Weight:305.333
Hs Code.:
DSSTox Substance ID:DTXSID801154426
ChEMBL ID:CHEMBL4531935
Mol file:343-70-4.mol

Synonyms:CHEMBL4531935;N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide;1-(4-fluorophenyl)-3-[(2-hydroxybenzoyl)amino]thiourea;DTXSID801154426;BDBM50520689;STK077405;AKOS000487816;343-70-4;AN-329/40396900;SR-01000321169;SR-01000321169-1;2-Hydroxybenzoic acid 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide;N-(4-fluorophenyl)-2-[(2-hydroxyphenyl)carbonyl]hydrazinecarbothioamide

Suppliers and Price of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Aronis compounds
N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide
5mg
$ 15.00

Total 0 raw suppliers

Chemical Property of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:305.06342597
Heavy Atom Count:21
Complexity:375

Purity/Quality:: N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NNC(=S)NC2=CC=C(C=C2)F)O

Technology Process of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide

There total 2 articles about N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 936-02-7
2-Hydroxybenzoylhydrazine

: 1544-68-9
4-fluorophenyl isothiocyanate

: 343-70-4
4-(4-fluorophenyl)-1-(2-hydroxybenzoyl)-3-thiosemicarbazide

Guidance literature:: In ethanol; for 0.25h; Reflux;
DOI:10.1111/cbdd.12392

Reference yield:

: 119-36-8,8024-54-2
methyl salicylate

: 343-70-4
4-(4-fluorophenyl)-1-(2-hydroxybenzoyl)-3-thiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 22 h / 760.05 Torr / Reflux

2: methanol / 5.5 h / 20 °C / 760.05 Torr

With hydrazine hydrate; In methanol; ethanol;
DOI:10.1016/j.ejmech.2018.09.067