Technology Process of dimethyl 5-[3-(2-hydroxy-5-methylphenyl)-3-oxopropanoyl]isophthalate
There total 8 articles about dimethyl 5-[3-(2-hydroxy-5-methylphenyl)-3-oxopropanoyl]isophthalate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; potassium hydroxide;
at 50 ℃;
for 1.5h;
DOI:10.1021/jm020839k
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 84 percent / K2CO3 / dimethylformamide / 14 h / 40 °C
2: 49 percent / LiOH / tetrahydrofuran; H2O / 2.5 h / 20 °C
3: SOCl2; DMF / Heating
4: 58 percent / pyridine / 0.5 h / 50 °C
5: 59 percent / pyridine; KOH / 1.5 h / 50 °C
With
pyridine; potassium hydroxide; lithium hydroxide; thionyl chloride; potassium carbonate; N,N-dimethyl-formamide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
4: Schotten-Baumann reaction / 5: Baker Venkataraman rearrangement;
DOI:10.1021/jm020839k
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 49 percent / LiOH / tetrahydrofuran; H2O / 2.5 h / 20 °C
2: SOCl2; DMF / Heating
3: 58 percent / pyridine / 0.5 h / 50 °C
4: 59 percent / pyridine; KOH / 1.5 h / 50 °C
With
pyridine; potassium hydroxide; lithium hydroxide; thionyl chloride; N,N-dimethyl-formamide;
In
tetrahydrofuran; water;
3: Schotten-Baumann reaction / 4: Baker Venkataraman rearrangement;
DOI:10.1021/jm020839k
