Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester

Base Information

Chemical Name:Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester
CAS No.:76812-02-7
Molecular Formula:C₃₄H₄₁NO₄
Molecular Weight:527.704
Hs Code.:
European Community (EC) Number:616-391-1
Nikkaji Number:J2.304.853A

Synonyms:Ethyl 4--alpha,alpha-dimethylbenzeneacetate hydrochloride;ethyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate;76812-02-7;Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester;ethyl 4-[4-(4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethylbenzeneacetate;ethyl 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethylbenzeneacetate;SCHEMBL48803;WUWWDNWDODGALA-UHFFFAOYSA-N;4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha, alpha-dimethylbenzeneacetic acid, ethyl ester;4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethylbenzeneacetic acid, ethyl ester;alpha,alpha-Dimethyl-4-[4-[4-(alpha-hydroxy-alpha-phenylbenzyl)piperidino]butyryl]benzeneacetic acid ethyl ester;ethyl 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]1-oxobutyl]-alpha,alpha-dimethylbenzeneacetate

Suppliers and Price of Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester

Chemical Property:

Boiling Point:666.3±55.0 °C(Predicted)
Density:1.121±0.06 g/cm3(Predicted)
XLogP3:6.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:12
Exact Mass:527.30355879
Heavy Atom Count:39
Complexity:748

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O

Technology Process of Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester

There total 2 articles about Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 169280-10-8
[4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester

: 115-46-8
C₁₈H₂₁NO

: 76812-02-7
4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid ethyl ester

Guidance literature:: With lithium perchlorate; In toluene; at 140 ℃; for 6h; Reagent/catalyst;

Reference yield:

: 76812-02-7
4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid ethyl ester

Guidance literature:

Reference yield: 98.0%

: 76812-02-7
4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid ethyl ester

: 138452-21-8,153439-40-8
fexofenadine hydrochloride

Guidance literature:: 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid ethyl ester; With sodium hydroxide; In methanol; water; for 2.25h; Heating / reflux;

With sodium tetrahydroborate; In methanol; water; at 20 - 35 ℃; for 49.44h;

With hydrogenchloride; In methanol; water; acetone; at -12 ℃; for 1.41667h;