N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester

Base Information

• Chemical Name: N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester
• CAS No.: 148730-17-0
• Molecular Formula: C₁₆H₁₅Cl₂N₃OS₂
• Molecular Weight: 400.353
• Mol file: 148730-17-0.mol

Synonyms:N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester

Chemical Property of N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester

There total 1 articles about N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 2-(2,6-dichloro-3-methylphenylamino)benzohydrazide + methyl iodide (74-88-4) → N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester (148730-17-0)

Guidance literature:

With potassium hydroxide; Yield given. Multistep reaction; 1.) MeOH, a) 0 deg C, 30 min, b) RT, 5 h, 2.) MeOH, RT, overnight;

DOI:10.1021/jm00065a002

Reference yield: 60.0%

N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester (148730-17-0) → 2,6-dichloro-3-methyl-N-<2-<5-(methylthio)-1,3,4-thiadiazol-2-yl>phenyl>benzenamine (133239-41-5)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 2h; Heating;

DOI:10.1021/jm00065a002

Reference yield:

N'-[2-(2,6-Dichloro-3-methyl-phenylamino)-benzoyl]-hydrazinecarbodithioic acid methyl ester (148730-17-0) → 2,6-dichloro-3-methyl-N-<2-<5-(methylsulfinyl)-1,3,4-thiadiazol-2-yl>phenyl>benzenamine (133239-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / p-TsOH / toluene / 2 h / Heating

2: 90 percent / m-chloroperbenzoic acid (mCPBA) / CH₂Cl₂ / 1 h / 0 °C

With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; toluene;

DOI:10.1021/jm00065a002

upstream raw materials:

carbon disulfide

methyl iodide

Downstream raw materials:

2,6-dichloro-3-methyl-N-<2-<5-(methylthio)-1,3,4-thiadiazol-2-yl>phenyl>benzenamine

2,6-dichloro-3-methyl-N-<2-<5-(methylsulfinyl)-1,3,4-thiadiazol-2-yl>phenyl>benzenamine