Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Base Information

Chemical Name:Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester
CAS No.:209069-80-7
Molecular Formula:C₁₅H₁₆N₄O₅S
Molecular Weight:364.382
Hs Code.:

Synonyms:Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Suppliers and Price of Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

There total 5 articles about Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 124-63-0
methanesulfonyl chloride

: 209069-74-9
9-(2-Hydroxy-ethyl)-1-methyl-8-phenyl-3,9-dihydro-purine-2,6-dione

: 209069-80-7
Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 - 25 ℃; for 1h;
DOI:10.1135/cccc19980407

Reference yield:

: 13300-31-7
6-(2-hydroxy-ethylamino)-3-methyl-5-nitroso-1H-pyrimidine-2,4-dione

: 209069-80-7
Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / H₂ / 10percent Pd/C / ethanol / 3 h / Ambient temperature

2: 60 percent / p-TsOH / dimethylformamide / 2 h / 100 °C

3: 88 percent / Et₃N / CH₂Cl₂ / 1 h / 20 - 25 °C

With hydrogen; toluene-4-sulfonic acid; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1135/cccc19980407

Reference yield:

: 13300-32-8
5-amino-6-(2-hydroxy-ethylamino)-3-methyl-1H-pyrimidine-2,4-dione

: 209069-80-7
Methanesulfonic acid 2-(1-methyl-2,6-dioxo-8-phenyl-1,2,3,6-tetrahydro-purin-9-yl)-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / p-TsOH / dimethylformamide / 2 h / 100 °C

2: 88 percent / Et₃N / CH₂Cl₂ / 1 h / 20 - 25 °C

With toluene-4-sulfonic acid; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1135/cccc19980407