2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate

Base Information

• Chemical Name: 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate
• CAS No.: 70905-69-0
• Molecular Formula: C₁₉H₂₆O₄
• Molecular Weight: 318.413
• Mol file: 70905-69-0.mol

Synonyms:2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate

Chemical Property of 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate

There total 10 articles about 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

<1R,4R,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate (152187-03-6) → 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate (70905-69-0)

Guidance literature:

With pyridine; trichlorophosphate; at 75 ℃; for 15h;

Reference yield: 64.0%

<1R,4S,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate (70905-70-3) → 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate (70905-69-0)

Guidance literature:

With pyridine; trichlorophosphate; at 75 - 80 ℃; for 20h;

DOI:10.1016/0957-4166(94)80179-7

Reference yield: 50.0%

<1R,4S,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate (70905-70-3) → 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate (70905-69-0) + Acetic acid (1R,5R)-4-[(E)-5-acetoxy-3-methyl-2-oxo-pent-3-en-(Z)-ylidene]-3,3,5-trimethyl-cyclohexyl ester (157942-40-0) + Acetic acid (1R,5R)-4-[(E)-5-acetoxy-3-methyl-2-oxo-pent-3-en-(E)-ylidene]-3,3,5-trimethyl-cyclohexyl ester (157942-46-6)

Guidance literature:

With toluene-4-sulfonic acid; tetrabutylammonium perrhenate; In dichloromethane; Ambient temperature;

DOI:10.1248/cpb.42.410

upstream raw materials:

<1R,4S,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate

<1R,4R,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate

(4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one

(1S,4R,6R)-1-<(E)-5-hydroxy-3-methylpent-3-en-1-ynyl>-2,2,6-trimethylcyclohexane-1,4-diol

Downstream raw materials:

(R)-4-<(E)-5-hydroxy-3-methylpent-3-en-1-ynyl>-3,5,5-trimethylcyclohex-3-enol

(2E,4E,6E,8E,10E)-13-((R)-4-Hydroxy-2,6,6-trimethyl-cyclohex-1-enyl)-2,7,11-trimethyl-trideca-2,4,6,8,10-pentaen-12-ynal

2-E-5-((4'R)-4'-hydroxy-2',2',6'-trimethylcyclohex-1'-enyl)-3-methyl-2-penten-4-yn-1-al