(3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

Base Information

• Chemical Name: (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• CAS No.: 122059-85-2
• Molecular Formula: C₁₈H₁₇N
• Molecular Weight: 247.34
• Mol file: 122059-85-2.mol

Synonyms:(3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

Chemical Property of (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

There total 7 articles about (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + (E)-N-benzylidenebenzenamine (1750-36-3,33993-35-0,538-51-2,137431-97-1,137432-04-3) → (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (122059-85-2)

Guidance literature:

erbium(III) triflate; In acetonitrile; for 20h; Product distribution; Ambient temperature; various catalysts;

DOI:10.1055/s-1995-4066

Reference yield: 96.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + benzaldehyde (100-52-7) + nitrobenzene (98-95-3,26969-40-4) → (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (122059-85-2)

Guidance literature:

With iron; citric acid; In water; at 40 ℃; for 4h; Reagent/catalyst; Concentration; Catalytic behavior; Sonication;

DOI:10.1021/jo502882y

Reference yield: 88.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + benzaldehyde (100-52-7) + aniline (62-53-3) → (3aS,4R,9bR)-rel-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (122059-85-2)

Guidance literature:

With montmorillonite K₁₀; In water; at 40 ℃; for 4h; Sonication;

DOI:10.1021/jo502882y

upstream raw materials:

cyclopenta-1,3-diene

(E)-N-benzylidenebenzenamine

benzaldehyde

aniline