(1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Base Information

• Chemical Name: (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate
• CAS No.: 1313587-28-8
• Molecular Formula: C₂₅H₃₈O₅
• Molecular Weight: 418.574

Synonyms:(1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Chemical Property of (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

There total 2 articles about (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H48O4Si + acetaldehyde (75-07-0,9002-91-9) → C25H38O5 (1313587-29-9) + (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate (1313587-28-8)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201100196

Reference yield:

(-)-(1Z,2S,3R,4S)-1-ethylidene-2,4-dimethyl-5-oxo-3-((1S)-1-phenylethoxy)-heptyl isobutyrate (767319-38-0) → C25H38O5 (1313587-29-9) + (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate (1313587-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / -20 - 20 °C / Inert atmosphere

2: boron trifluoride diethyl etherate / dichloromethane / -78 °C / Inert atmosphere

With boron trifluoride diethyl etherate; triethylamine; In dichloromethane;

DOI:10.1002/ejoc.201100196

Reference yield: 90.0%

(1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate (1313587-28-8) + acetaldehyde (75-07-0,9002-91-9) → (1Z,2S,3S,4S,5R,6S,7R)-7-acetoxy-1-ethylidene-3-hydroxy-2,4,6-trimethyl-5-[(1S)-1-phenylethoxy]octyl isobutyrate (1313587-34-6)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at -20 ℃; for 18h; Inert atmosphere; Darkness;

DOI:10.1002/ejoc.201100196

upstream raw materials:

acetaldehyde

(-)-(1Z,2S,3R,4S)-1-ethylidene-2,4-dimethyl-5-oxo-3-((1S)-1-phenylethoxy)-heptyl isobutyrate

Downstream raw materials:

(1Z,2S,3S,4R,5R,6S,7R)-1-ethylidene-5,7-dihydroxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

(1Z,2S,3S,4R,5R,6R,7S)-1-ethylidene-5-hydroxy-7-(4-nitrobenzoyloxy)-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

(1Z,2S,3R,4S,6S,7S)-1-ethylidene-7-(4-nitrobenzoyloxy)-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

(2S,3R)-3-{(4S,5R,6S)-6-[(S,Z)-3-(isobutyryloxy)pent-3-en-2-yl]-2,2,5-trimethyl-1,3-dioxan-4-yl}but-2-yl 4-nitrobenzoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1313587-28-8 (1Z,2S,3R,4S,6S,7R)-1-ethylidene-7-hydroxy-2,4,6-trimethyl-5-oxo-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Send

Send

Metric Ton KG G Pound L ML

Send

Send