4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

Base Information

Chemical Name:4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide
CAS No.:934808-03-4
Molecular Formula:C₂₂H₂₉N₃O₂
Molecular Weight:367.491
Hs Code.:

Synonyms:4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

Suppliers and Price of 4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

There total 1 articles about 4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 934808-02-3
4-(2-allyl-piperidin-1-yl)-4-oxo-butyric acid

: 706-03-6
3-(benzylamino)propionitrile

: 934808-03-4
4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

Guidance literature:: With dmap; benzoic acid anhydride; triethylamine; In dichloromethane; at 20 ℃; for 25h;
DOI:10.1016/j.tet.2007.01.068

Reference yield: 87.0%

: 934808-03-4
4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

: 934808-00-1
N¹-[4-((S)-2-allyl-piperidin-1-yl)-butyl]-N¹-benzyl-propane-1,3-diamine

Guidance literature:: With lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran; at 25 ℃; for 3h;
DOI:10.1016/j.tet.2007.01.068

Reference yield:

: 934808-03-4
4-((S)-2-allyl-piperidin-1-yl)-N-benzyl-N-(2-cyanoethyl)-4-oxo-butyramide

: 934808-06-7
9-benzyl-1,3,4,6,7,8,9,10,11,12,13,15,16,17,18,19,20,21,24,24a-eicosahydro-2H,5H-4a,9,13-triaza-benzocyclodocosen-14-one

Guidance literature:: Multi-step reaction with 3 steps

1: lithium aluminum hydride / 25 °C

2: 276 mg / triethylamine / CH₂Cl₂ / 2 h / 0 °C

3: 65 percent / aq. HCl / Grubbs' second-generation catalyst / CH₂Cl₂ / 14 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; triethylamine; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; 1: retro-Michael addition;
DOI:10.1016/j.tet.2007.01.068