(3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol

Base Information

• Chemical Name: (3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol
• CAS No.: 82792-84-5
• Molecular Formula: C₁₈H₂₂O₆
• Molecular Weight: 334.369
• Mol file: 82792-84-5.mol

Synonyms:(3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol

Chemical Property of (3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol

There total 1 articles about (3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4,5-dimethoxybenzyl alcohol (54370-00-2) + 3,4-dimethoxy-benzaldehyde (120-14-9) → (3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol (82792-84-5)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) THF, -78 deg C;

DOI:10.1039/c39820000430

Reference yield:

(3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol (82792-84-5) → (3aR,4R,9aS)-4-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-3a,4,9,9a-tetrahydro-naphtho[2,3-c]furan-1,3-dione

Guidance literature:

Multi-step reaction with 3 steps

2: 40percent peracetic acid

3: 70 percent / various solvent(s) / 3 h / 170 - 210 °C

With peracetic acid; In various solvent(s);

DOI:10.1039/c39820000430

Reference yield:

(3,4-Dimethoxy-phenyl)-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-methanol (82792-84-5) → (1R,2R)-1-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

Guidance literature:

Multi-step reaction with 3 steps

2: 40percent peracetic acid

3: various solvent(s) / 0.33 h / 200 °C / sealed tube

With peracetic acid; In various solvent(s);

DOI:10.1039/c39820000430

upstream raw materials:

2-bromo-4,5-dimethoxybenzyl alcohol

3,4-dimethoxy-benzaldehyde

Downstream raw materials:

1-(3,4-Dimethoxy-phenyl)-5,6-dimethoxy-1,3-dihydro-benzo[c]thiophene

dimethyl trans(1,2),trans(2,3)-6,7-dimethoxy-1-(3,4-dimethoxyphenyl)-1,3,4-tetrahydronaphthalene-2,3-dicarboxylate

(+/-)-phyltetralin

1-(3,4-Dimethoxy-phenyl)-5,6-dimethoxy-1,3-dihydro-benzo[c]thiophene 2,2-dioxide