Technology Process of 1,3,2’,6’-tetraazido-5,6,3’-tri-O-benzylneamine
There total 9 articles about 1,3,2’,6’-tetraazido-5,6,3’-tri-O-benzylneamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium azide;
In
N,N-dimethyl-formamide;
at 70 ℃;
for 15h;
Inert atmosphere;
DOI:10.1039/c4md00072b
- Guidance literature:
-
Multi-step reaction with 6 steps
1: triflic azide; copper(ll) sulfate pentahydrate; triethylamine / Inert atmosphere
2: camphorsulfonic acid / N,N-dimethyl-formamide / Inert atmosphere
3: sodium hydride / N,N-dimethyl-formamide / Inert atmosphere
4: acetic acid / water / 60 °C / Inert atmosphere
5: pyridine / Inert atmosphere
6: sodium azide / N,N-dimethyl acetamide / Inert atmosphere
With
pyridine; sodium azide; copper(ll) sulfate pentahydrate; triflic azide; sodium hydride; acetic acid; triethylamine;
In
N,N-dimethyl acetamide; water; N,N-dimethyl-formamide;
DOI:10.1002/cbic.201800549
-
-
289505-10-8
(2R,3S,4R,5R,6S)-5-azido-6-(((1R,2R,3S,4R,6S)-4, 6-diazido-2,3-dihydroxycyclohexyl)oxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: (1S)-10-camphorsulfonic acid / 1,2-dichloro-ethane / 2 h / Reflux; Inert atmosphere
2.1: sodium hydride / mineral oil; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
2.2: 0 - 26 °C
3.1: acetic acid; water / tetrahydrofuran / 60 °C / Inert atmosphere
4.1: pyridine / dichloromethane / 22 - 26 °C / Inert atmosphere
5.1: sodium azide / N,N-dimethyl-formamide / 15 h / 70 °C / Inert atmosphere
With
pyridine; sodium azide; (1S)-10-camphorsulfonic acid; water; sodium hydride; acetic acid;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1039/c4md00072b
