tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Base Information

Chemical Name:tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate
CAS No.:1519044-14-4
Molecular Formula:C₂₇H₂₈N₂O₅S₂
Molecular Weight:524.662
Hs Code.:

Synonyms:tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Suppliers and Price of tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

There total 4 articles about tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 1519044-06-4
tert-butyl 2-(3-bromothiophene-2-sulfonamido)ethylcarbamate

: 1519044-13-3
2-(naphthalen-1-yloxy)phenylboronic acid

: 1519044-14-4
tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In tetrahydrofuran; for 8h; Inert atmosphere; Reflux;
DOI:10.1002/cmdc.201400058

Reference yield:

: 57260-73-8
N-BOC-1,2-diaminoethane

: 1519044-14-4
tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1.08 h / 0 - 20 °C

2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran / 8 h / Inert atmosphere; Reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; In tetrahydrofuran; dichloromethane; 2: |Suzuki Coupling;
DOI:10.1002/cmdc.201400058

Reference yield:

: 1519044-12-2
1-(2-iodophenoxy)naphthalene

: 1519044-14-4
tert-butyl 2-(3-(2-(naphthalen-1-yloxy)phenyl)thiophene-2-sulfonamido)ethylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

1.2: 4 h / -78 - 20 °C / Inert atmosphere

1.3: 20 °C

2.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran / 8 h / Inert atmosphere; Reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; n-butyllithium; palladium diacetate; In tetrahydrofuran; 2.1: |Suzuki Coupling;
DOI:10.1002/cmdc.201400058