ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate

Base Information

• Chemical Name: ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate
• CAS No.: 126059-05-0
• Molecular Formula: C₂₃H₂₅NO₆
• Molecular Weight: 411.455
• Mol file: 126059-05-0.mol

Synonyms:ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate

Chemical Property of ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate

There total 5 articles about ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

benzoyl chloride (98-88-4) + ethyl 2-butyryl-3-<(4-hydroxy-2-methoxyphenyl)amino>acrylate (126059-04-9) → ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate (126059-05-0)

Guidance literature:

With pyridine; In dichloromethane; Ambient temperature;

DOI:10.1021/jm00014a026

Reference yield:

O-methylresorcine (150-19-6) → ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate (126059-05-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) NaNO₂, sulfanilic acid, Na₂CO₃, 2.) aq. NaOH, 3.) sodium dithionite

2: 45 percent / 0.17 h / 100 °C

3: 52 percent / pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; sodium hydroxide; sodium dithionite; sodium carbonate; sodium nitrite; 4-aminobenzene sulfonic acid; In dichloromethane;

DOI:10.1021/jm00014a026

Reference yield:

4-Amino-3-methoxyphenol (61638-01-5) → ethyl 2-butyryl-3-<<4-(benzoyloxy)-2-methoxyphenyl>amino>acrylate (126059-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / 0.17 h / 100 °C

2: 52 percent / pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; In dichloromethane;

DOI:10.1021/jm00014a026

upstream raw materials:

benzoyl chloride

ethyl 2-butyryl-3-<(4-hydroxy-2-methoxyphenyl)amino>acrylate

O-methylresorcine

4-Amino-3-methoxyphenol

Downstream raw materials:

3-butyryl-6-benzoyloxy-4-chloro-8-methoxyquinoline

3-butyryl-6-benzoyloxy-8-methoxy-4(1H)-quinolone