methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide

Base Information

• Chemical Name: methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide
• CAS No.: 345319-22-4
• Molecular Formula: C₁₈H₁₆N₂O₄S
• Molecular Weight: 356.402
• Mol file: 345319-22-4.mol

Synonyms:methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide

Chemical Property of methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide

There total 1 articles about methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzofurazan oxide (480-96-6,68100-26-5) + methyl 3-oxo-5-(phenylthio)pentanoate (51849-20-8) → methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide (345319-22-4)

Guidance literature:

With calcium hydroxide; In chloroform; isopropyl alcohol; at 60 ℃; for 2h;

DOI:10.1021/jm00349a021

Reference yield:

methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide (345319-22-4) → methyl 3-<2-(phenylsulfonyl)ethyl>quinoxaline-2-carboxylate 1,4-dioxide (82032-59-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 0.5h; Yield given; Ambient temperature;

DOI:10.1021/jm00349a021

Reference yield:

methyl 3-<2-(phenylthio)ethyl>quinoxaline-2-carboxylate 1,4-dioxide (345319-22-4) → 2-Cyclohexyl-5,10-dioxy-3,4-dihydro-2H-pyrido[3,4-b]quinoxalin-1-one

Guidance literature:

Multi-step reaction with 2 steps

1: m-chloroperbenzoic acid / CHCl₃ / 0.5 h / Ambient temperature

2: 59 percent / acetonitrile / 36 h / Ambient temperature

With 3-chloro-benzenecarboperoxoic acid; In chloroform; acetonitrile;

DOI:10.1021/jm00349a021

upstream raw materials:

benzofurazan oxide

methyl 3-oxo-5-(phenylthio)pentanoate

Downstream raw materials:

methyl 3-<2-(phenylsulfonyl)ethyl>quinoxaline-2-carboxylate 1,4-dioxide