C₃₀H₄₃NO₄SSi

Base Information

• Chemical Name: C₃₀H₄₃NO₄SSi
• CAS No.: 1438399-34-8
• Molecular Formula: C₃₀H₄₃NO₄SSi
• Molecular Weight: 541.827
• Mol file: 1438399-34-8.mol

Synonyms:C₃₀H₄₃NO₄SSi

Chemical Property of C₃₀H₄₃NO₄SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₃₀H₄₃NO₄SSi

There total 5 articles about C₃₀H₄₃NO₄SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

C10H18NO2S(1+)*ClO4(1-) (1195778-13-2) + (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal (91751-24-5,92817-88-4,123284-89-9,112897-04-8) → C30H43NO4SSi (1438399-34-8)

Guidance literature:

C₁₀H₁₈NO₂S⁽¹⁺⁾*ClO₄^(1-); With sodium hydroxide; In water; for 0.5h;

(R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal; In dichloromethane; water; at 25 ℃; for 48h;

DOI:10.1002/chem.201201332

Reference yield:

C10H18ClNO2S → C30H43NO4SSi (1438399-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium perchlorate / acetone / 48 h / 40 °C / Inert atmosphere

2.1: sodium hydroxide / water / 0.5 h

2.2: 48 h / 25 °C

With sodium perchlorate; sodium hydroxide; In water; acetone;

DOI:10.1002/chem.201201332

Reference yield:

L-methionine (63-68-3,26062-47-5,58576-49-1) → C30H43NO4SSi (1438399-34-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 25.5 h / Reflux; Inert atmosphere

1.2: 6 h / Reflux; Inert atmosphere

2.1: camphor-10-sulfonic acid / 12 h / Molecular sieve; Reflux; Inert atmosphere

3.1: triethylamine / dichloromethane / 0.58 h / 0 °C / Inert atmosphere

4.1: sodium perchlorate / acetone / 48 h / 40 °C / Inert atmosphere

5.1: sodium hydroxide / water / 0.5 h

5.2: 48 h / 25 °C

With sodium tetrahydroborate; camphor-10-sulfonic acid; sodium perchlorate; iodine; triethylamine; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; acetone;

DOI:10.1002/chem.201201332

upstream raw materials:

C₁₀H₁₈NO₂S⁽¹⁺⁾*ClO₄^(1-)

(R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal

L-methionine

(S)-methioninol

Downstream raw materials:

((2R,3R)-3-((R)-1-((tert-butyldiphenylsilyl)oxy)propan-2-yl)oxiran-2-yl)methanol