1,1,2-Triphenyl-2-(phenylamino)ethan-1-ol

Base Information

• Chemical Name: 1,1,2-Triphenyl-2-(phenylamino)ethan-1-ol
• CAS No.: 131699-30-4
• Molecular Formula: C₂₆H₂₃NO
• Molecular Weight: 365.475
• European Community (EC) Number: 659-076-4
• Nikkaji Number: J1.368.311E
• Mol file: 131699-30-4.mol

Synonyms:1,1,2-triphenyl-2-(phenylamino)ethan-1-ol;2-anilino-1,1,2-triphenylethanol;131699-30-4;SCHEMBL9826906;1,1,2-Triphenyl-2-anilinoethanol;AKOS024434332

Chemical Property of 1,1,2-Triphenyl-2-(phenylamino)ethan-1-ol

Chemical Property:

• XLogP3: 5.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 365.177964357
• Heavy Atom Count: 28
• Complexity: 421

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)(C3=CC=CC=C3)O)NC4=CC=CC=C4

Technology Process of 1,1,2-Triphenyl-2-(phenylamino)ethan-1-ol

There total 3 articles about 1,1,2-Triphenyl-2-(phenylamino)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

benzophenone (119-61-9) + benzylidene phenylamine (538-51-2) → 1,1-Diphenyl-2-phenylamino-2-phenylethanol (131699-30-4)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 65 ℃; for 5h;

Reference yield: 71.0%

benzophenone (119-61-9) + α,N-Diphenyl-1H-benzotriazole-1-methanamine (142943-95-1) → 1,1-Diphenylmethanol (91-01-0) + 1,1-Diphenyl-2-phenylamino-2-phenylethanol (131699-30-4)

Guidance literature:

benzophenone; With ytterbium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃;

α,N-Diphenyl-1H-benzotriazole-1-methanamine; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(02)00235-6

Reference yield:

1,2-diphenyl-2-(phenylamino)ethanone (5722-91-8) + phenylmagnesium bromide → 1,1-Diphenyl-2-phenylamino-2-phenylethanol (131699-30-4)

Guidance literature:

With diethyl ether;

DOI:10.1039/jr9380000206

upstream raw materials:

1,2-diphenyl-2-(phenylamino)ethanone

benzophenone

benzylidene phenylamine

α,N-Diphenyl-1H-benzotriazole-1-methanamine

Downstream raw materials:

1,2,2-triphenylethan-1-one