Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Base Information

Chemical Name:Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester
CAS No.:203389-79-1
Molecular Formula:C₃₃H₃₅O₇P
Molecular Weight:574.61
Hs Code.:

Synonyms:Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Suppliers and Price of Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

There total 6 articles about Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 203389-78-0
Phosphoric acid dibenzyl ester (2R,3R)-2,3-bis-benzyloxy-4-hydroxy-pentyl ester

: 203389-79-1
Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Guidance literature:: With Dess-Martin periodane; In dichloromethane; for 12h; Ambient temperature;
DOI:10.1021/jo971933p

Reference yield:

: 100-39-0
benzyl bromide

: 203389-79-1
Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 88 percent / thallous ethoxide / acetonitrile / 1.) 55 deg C, 48 h, 2.) room temp., 12 h

2: 83.3 percent / LiAlH₄ / tetrahydrofuran / 3 h / Ambient temperature

3: 40 percent / CCl₄; pyridine / 12 h / Ambient temperature

4: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -10 deg C, 10 min, 2.) CH₂Cl₂, -10 deg C, 5 min

6: 74 percent / Dess-Martin reagent / CH₂Cl₂ / 12 h / Ambient temperature

With lithium aluminium tetrahydride; oxalyl dichloride; thallium (I) ethoxide; Dess-Martin periodane; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; pyridine; tetrachloromethane; dichloromethane; acetonitrile;
DOI:10.1021/jo971933p

Reference yield:

: 113350-84-8
(2R,3R)-(-)-2,3-bis(phenylmethoxy)-1,4-butanediol

: 203389-79-1
Phosphoric acid dibenzyl ester (2R,3S)-2,3-bis-benzyloxy-4-oxo-pentyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 40 percent / CCl₄; pyridine / 12 h / Ambient temperature

2: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -10 deg C, 10 min, 2.) CH₂Cl₂, -10 deg C, 5 min

4: 74 percent / Dess-Martin reagent / CH₂Cl₂ / 12 h / Ambient temperature

With oxalyl dichloride; Dess-Martin periodane; dimethyl sulfoxide; triethylamine; In pyridine; tetrachloromethane; dichloromethane;
DOI:10.1021/jo971933p