(2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane

Base Information

• Chemical Name: (2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane
• CAS No.: 174002-46-1
• Molecular Formula: C₁₈H₁₈O₄S
• Molecular Weight: 330.405
• Mol file: 174002-46-1.mol

Synonyms:(2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane

Chemical Property of (2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane

There total 1 articles about (2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoic acid (65-85-0,8013-63-6) + (RS)-2-hydroxymethyl-2-<<(4-methylphenyl)sulfinyl>methyl>oxirane → (2R)-2-benzoyloxymethyl-2-<(4-methylphenyl)sulfinyl>methyl oxirane (174173-69-4) + (2S,RS)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane (174002-46-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 4.5h; Yield given. Yields of byproduct given;

DOI:10.1016/0957-4166(95)00359-W

Reference yield: 96.0%

(2S,RS)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane (174002-46-1) → Benzoic acid (S)-2-chloromethyl-2-hydroxy-3-((R)-toluene-4-sulfinyl)-propyl ester

Guidance literature:

With lithium chloride; copper dichloride; In tetrahydrofuran; at 25 ℃; for 2h;

DOI:10.1016/0957-4166(96)00042-0

Reference yield: 62.0%

(2S,RS)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane (174002-46-1) → (2S,RS)-2-<<(4-methylphenyl)sulfinyl>methyl>-3-O-benzoyl-propan-1,2,3-triol (174002-52-9)

Guidance literature:

With perchloric acid; In tetrahydrofuran; water; at 40 ℃; for 48h;

DOI:10.1016/0957-4166(95)00359-W

upstream raw materials:

benzoic acid

Downstream raw materials:

(2S,R_S)-2-<<(4-methylphenyl)sulfinyl>methyl>-3-O-benzoyl-propan-1,2,3-triol

(S)-2-benzoyloxy-2-hydroxymethyl oxirane

(S)-2-benzoyloxymethyl-2-formyl oxirane

(S)-2-<<(4-methylphenyl)sulfenyl>methyl>-3-O-benzoyl-propan-1,2,3-triol