Methylprednisolone Ethylothopropionate

Base Information

Chemical Name:Methylprednisolone Ethylothopropionate
CAS No.:85198-27-2
Molecular Formula:C₂₇H₃₈O₆
Molecular Weight:458.595
Hs Code.:
UNII:JWK84KY9SU

Synonyms:Methylprednisolone Ethylothopropionate;JWK84KY9SU;SCHEMBL10908149;(6alpha,11beta)-17,21-[(1-Ethoxypropylidene)bis(oxy)]-11-hydroxy-6-methylpregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 17,21-[(1-ethoxypropylidene)bis(oxy)]-11-hydroxy-6-methyl-, (6alpha,11beta)-

Suppliers and Price of Methylprednisolone Ethylothopropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6α-MethylPrednisolone17,21-(Ethyl)orthopropionate
5g
$ 1320.00

TRC
6α-MethylPrednisolone17,21-(Ethyl)orthopropionate
500mg
$ 165.00

Medical Isotopes, Inc.
6α-MethylPrednisolone17,21-(Ethyl)orthopropionate
5 g
$ 2200.00

Total 6 raw suppliers

Chemical Property of Methylprednisolone Ethylothopropionate

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:458.26683893
Heavy Atom Count:33
Complexity:924

Purity/Quality:

> 95% ^*data from raw suppliers

6α-MethylPrednisolone17,21-(Ethyl)orthopropionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(OCC(=O)C2(O1)CCC3C2(CC(C4C3CC(C5=CC(=O)C=CC45C)C)O)C)OCC
Isomeric SMILES:CCC1(OCC(=O)[C@@]2(O1)CC[C@@H]3[C@@]2(C[C@@H]([C@H]4[C@H]3C[C@@H](C5=CC(=O)C=C[C@]45C)C)O)C)OCC
Uses 6α-Methyl Prednisolone 17,21-(Ethyl)orthopropionate is an impurity of 6α-Methyl Prednisolone (M325934), a glucocorticoid which displays anti-inflamatory and antioxidant properties and attenuates apoptosis in oligodendrocytes after injury. 6α-Methyl Prednisolone is neuroprotective.

Technology Process of Methylprednisolone Ethylothopropionate

There total 3 articles about Methylprednisolone Ethylothopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 103744-18-9
(6S,8S,9S,10R,11S,13S,14S,17S)-11-Hydroxy-17-(2-hydroxy-acetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one

: 115-80-0
Triethyl orthopropionate

: 85198-27-2
6α-Methylprednisolone 17α,21-ethyl orthopropanoate

Guidance literature:: With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 85 ℃; for 1.5h;
DOI:10.1055/s-1982-30048

Reference yield:

: 83-43-2
Methylprednisolone

: 85198-27-2
6α-Methylprednisolone 17α,21-ethyl orthopropanoate

Guidance literature:: With pyridine; In N-methyl-acetamide; benzene;

Reference yield:

: 83-43-2
Methylprednisolone

: 115-80-0
Triethyl orthopropionate

: 85198-27-2
6α-Methylprednisolone 17α,21-ethyl orthopropanoate

Guidance literature:: With sodium carbonate; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1.) DMF, 70-90 deg C, 2.) DMF, water, ethyl acetate;
DOI:10.1248/cpb.31.12