phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside

Base Information

• Chemical Name: phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside
• CAS No.: 849132-40-7
• Molecular Formula: C₃₅H₃₀O₉S₂
• Molecular Weight: 658.75
• Mol file: 849132-40-7.mol

Synonyms:phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside

Chemical Property of phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside

There total 6 articles about phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

phenyl 4-O-acetyl-2,6-di-O-benzoyl-1-thio-β-thio-β-D-galactopyranoside (152488-28-3) + phenylcarbonochloridothioate (1005-56-7) → phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside (849132-40-7)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.tetasy.2004.12.004

Reference yield:

1-thiophenyl-β-D-galactopyranoside (16758-34-2) → phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside (849132-40-7)

Guidance literature:

Multi-step reaction with 5 steps

1.1: CSA

2.1: pyridine / CH₂Cl₂

3.1: AcOH; H₂O

4.1: trifluoroacetic acid / CHCl₃ / 0.08 h / 20 °C

4.2: 95 percent / H₂O / acetonitrile; CHCl₃ / 0.5 h / 20 °C

5.1: 79 percent / pyridine / CH₂Cl₂ / 24 h / 20 °C

With pyridine; camphor-10-sulfonic acid; water; acetic acid; trifluoroacetic acid; In dichloromethane; chloroform;

DOI:10.1016/j.tetasy.2004.12.004

Reference yield:

benzoyl chloride (98-88-4) → phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-phenoxythiocarbonyl-1-thio-β-D-galactoside (849132-40-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: pyridine / CH₂Cl₂

2.1: AcOH; H₂O

3.1: trifluoroacetic acid / CHCl₃ / 0.08 h / 20 °C

3.2: 95 percent / H₂O / acetonitrile; CHCl₃ / 0.5 h / 20 °C

4.1: 79 percent / pyridine / CH₂Cl₂ / 24 h / 20 °C

With pyridine; water; acetic acid; trifluoroacetic acid; In dichloromethane; chloroform;

DOI:10.1016/j.tetasy.2004.12.004

upstream raw materials:

phenyl 4-O-acetyl-2,6-di-O-benzoyl-1-thio-β-thio-β-D-galactopyranoside

phenylcarbonochloridothioate

1-thiophenyl-β-D-galactopyranoside

benzoyl chloride

Downstream raw materials:

phenyl 4-O-acetyl-2,6-di-O-benzoyl-3-deoxy-1-thio-β-D-xylo-hexoside

phenyl 2,6-di-O-benzoyl-4-O-chloroacetyl-3-deoxy-1-thio-β-D-ribo-hexoside

phenyl 2,6-di-O-benzoyl-3-deoxy-1-thio-β-D-xylo-hexopyranoside

phenyl 2,6-di-O-benzoyl-3-deoxy-1-thio-β-D-ribo-hexopyranoside