trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate

Base Information

• Chemical Name: trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate
• CAS No.: 82725-54-0
• Molecular Formula: C₁₅H₂₀O₃
• Molecular Weight: 248.322
• Mol file: 82725-54-0.mol

Synonyms:trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate

Chemical Property of trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate

There total 1 articles about trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

trans-2-(2-hydroxyethyl)cyclohexanol (27345-72-8) + benzoyl chloride (98-88-4) → trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate (82725-54-0)

Guidance literature:

In pyridine; diethyl ether; 1) 1 h, -40 deg C; 2) 6 h, -5 deg C;

Reference yield: 92.0%

trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate (82725-54-0) → 2-(2-Benzoyloxyethyl)cyclohexanone (82725-55-1)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 4h;

Reference yield:

trans-2-(2-Hydroxyethyl)cyclohexanol monobenzoate (82725-54-0) → trans-<1-(2)H>-2-(2-Hydroxyethyl)cyclohexanol (82725-58-4,82725-59-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / Pyridinium chlorochromate / CH₂Cl₂ / 4 h

2: 1.3 g / NaBD₄ / ethanol / 0.5 h / 0 °C

3: 93 percent / KOH / methanol; H₂O / 6 h / Heating

With potassium hydroxide; sodium borodeuteride; pyridinium chlorochromate; In methanol; ethanol; dichloromethane; water;

upstream raw materials:

trans-2-(2-hydroxyethyl)cyclohexanol

benzoyl chloride

Downstream raw materials:

2-(2-Benzoyloxyethyl)cyclohexanone

trans-<1-(2)H>-2-(2-Hydroxyethyl)cyclohexanol

cis-<1-(2)H>-2-(2-Hydroxyethyl)cyclohexanol

cis-<1-(2)H>-2-(2-Benzoyloxyethyl)cyclohexanol