(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

Base Information

Chemical Name:(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal
CAS No.:238421-67-5
Molecular Formula:C₂₉H₄₄O₅Si
Molecular Weight:500.751
Hs Code.:

Synonyms:(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

Suppliers and Price of (4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

There total 1 articles about (4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: (2R,4S)-2-(2-[1,3]Dioxolan-2-yl-ethyl)-2,5-dimethyl-hexane-1,3,4-triol

: 238421-67-5
(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 3h;

Reference yield: 48.0%

: 238421-67-5
(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

: 238421-68-6
(2R)-2-(tert-butyldiphenylsilyloxymethyl)-2-methylpentanedial 5-ethylene acetal

Guidance literature:: With sodium periodate; In 1,4-dioxane; water; at 20 ℃; for 6h;

Reference yield:

: 238421-67-5
(4R,6S)-4-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydroxy-4,7-dimethyloctanal ethylene acetal

: 4-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-5-oxo-heptanal

Guidance literature:: Multi-step reaction with 4 steps

1: 48 percent / NaIO₄ / H₂O; dioxane / 6 h / 20 °C

2: tetrahydrofuran / 3 h / 20 °C

3: 61 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

4: p-TsOH*H₂O; acetone / 18 h / Heating

With sodium periodate; oxalyl dichloride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; acetone; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; 1: Oxidation / 2: Grignard reaction / 3: Dehydrogenation / 4: deacetalization;