Cyclohexanone, 3-acetyl-3-methyl- (9CI)

Base Information

• Chemical Name: Cyclohexanone, 3-acetyl-3-methyl- (9CI)
• CAS No.: 173547-35-8
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.209
• Mol file: 173547-35-8.mol

Synonyms:3-Acetyl-3-methylcyclohexanone

Chemical Property of Cyclohexanone, 3-acetyl-3-methyl- (9CI)

Chemical Property:

• PSA: 34.14000
• LogP: 1.72480

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanone, 3-acetyl-3-methyl- (9CI)

There total 4 articles about Cyclohexanone, 3-acetyl-3-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methylcyclohexen-2-one (1193-18-6) → 3-Acetyl-3-methylcyclohexanone (173547-35-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / benzyltriethylammonium chloride / benzene

2: aq. KMnO₄, KOH, MgSO₄ / methanol / 1.) r.t., 2. ) reflux

With potassium hydroxide; potassium permanganate; magnesium sulfate; potassium carbonate; N-benzyl-N,N,N-triethylammonium chloride; In methanol; benzene;

DOI:10.1071/CH9951827

Reference yield:

(+/-)-3-methyl-3-(1'-nitroethyl)cyclohexanone (173547-32-5) → 3-Acetyl-3-methylcyclohexanone (173547-35-8)

Guidance literature:

With potassium hydroxide; potassium permanganate; magnesium sulfate; In methanol; 1.) r.t., 2. ) reflux;

DOI:10.1071/CH9951827

Reference yield:

C26H34O4 → 3-Acetyl-3-methylcyclohexanone (173547-35-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiNH₂ / liquid ammonia; ethanol; diethyl ether

2: (i) O₃, (ii) Zn, AcOH

With lithium amide; In diethyl ether; ethanol; ammonia;

upstream raw materials:

rac.2-(1-Methyl-4-oxo-cyclohexyl)-3-(1-methyl-3-oxo-cyclohexyl)-trans-buten-⁽²⁾

(+/-)-3-methyl-3-(1'-nitroethyl)cyclohexanone

3-methylcyclohexen-2-one

Downstream raw materials:

3-methyl-oct-7-en-2-one

methyl 1-methylcyclohexyl ketone

Refernces