(S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: (S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1201898-77-2
• Molecular Formula: C₁₇H₂₅BO₂
• Molecular Weight: 272.195
• Mol file: 1201898-77-2.mol

Synonyms:(S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of (S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 1 articles about (S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (72824-04-5) + (S)-(-)-1-phenylethyl N,N-diisopropylcarbamate (133038-74-1) → (S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1201898-77-2)

Guidance literature:

(S)-(-)-1-phenylethyl N,N-diisopropylcarbamate; With sec.-butyllithium; In diethyl ether; hexane; cyclohexane; at -75 - -70 ℃; for 0.416667h; Inert atmosphere;

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In diethyl ether; hexane; cyclohexane; at -70 - 25 ℃; for 4.75h; Inert atmosphere;

DOI:10.1016/j.tet.2009.10.002

Reference yield: 99.0%

(S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1201898-77-2) → potassium (S)-(2-phenylpent-4-en-2-yl)trifluoroborate

Guidance literature:

With potassium hydrogenfluoride; water; In methanol; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.10.002

Reference yield: 98.0%

(S)-2-(2-phenylpent-4-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1201898-77-2) → (S)-pent-4-en-2-ylbenzene (78330-53-7)

Guidance literature:

With tetrabutyl ammonium fluoride; In pentane; at 45 ℃; for 2h;

DOI:10.1021/ja1084207

upstream raw materials:

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

(S)-(-)-1-phenylethyl N,N-diisopropylcarbamate

Downstream raw materials:

(R)-2-phenyl-pent-4-en-2-ol

(S)-pent-4-en-2-ylbenzene

(+)-2-methyl-2-phenylbutane-1,4-diol

(S)-(3-methylhexa-1,5-dien-3-yl)benzene