1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol

Base Information

• Chemical Name: 1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol
• CAS No.: 244262-39-3
• Molecular Formula: C₁₉H₂₂N₂O₇
• Molecular Weight: 390.393
• Mol file: 244262-39-3.mol

Synonyms:1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol

Chemical Property of 1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol

There total 1 articles about 1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4,4'-dimethoxy-3,3'-dimethoxycarbonyl-5,5'-dinitrobenzophenone (207743-22-4) → 1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol (244262-39-3)

Guidance literature:

With acetic acid; zinc; at 45 ℃; for 1h;

DOI:10.1021/jo990177f

Reference yield:

1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol (244262-39-3) → 3,3'-bis(4-methoxy-3-methoxycarbonylbenzamido)-4,4'-dimethoxy-5,5'-dimethoxycarbonylbenzophenone (244262-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂

2: 85 percent / CrO₃ / 3 h / 0 °C

With pyridine; chromium(VI) oxide; In dichloromethane; 1: Acylation / 2: Oxidation;

DOI:10.1021/jo990177f

Reference yield:

1,1'-bis(3-amino-4-methoxy-5-methoxycarbonylphenyl)methanol (244262-39-3) → 5α,3β-[4',4'-(3,3-bis[3'''-methoxy-4'''-methoxycarbonylbenzamido]-4,4-dimethoxy-5,5-dimethoxycarbonyldiphenyl)-3'-butenyl]cholestane (244262-75-7)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂

2: 85 percent / CrO₃ / 3 h / 0 °C

3: 25 percent / TiCl₄*2H₂O; Zn dust / tetrahydrofuran / 1 h / Heating

With pyridine; chromium(VI) oxide; titanium tetrachloride; zinc; In tetrahydrofuran; dichloromethane; 1: Acylation / 2: Oxidation / 3: Condensation;

DOI:10.1021/jo990177f

upstream raw materials:

4,4'-dimethoxy-3,3'-dimethoxycarbonyl-5,5'-dinitrobenzophenone

Downstream raw materials:

3,3'-bis(4-methoxy-3-methoxycarbonylbenzamido)-4,4'-dimethoxy-5,5'-dimethoxycarbonylbenzophenone

5α,3β-[4',4'-(3,3-bis[3'''-methoxy-4'''-methoxycarbonylbenzamido]-4,4-dimethoxy-5,5-dimethoxycarbonyldiphenyl)-3'-butenyl]cholestane