40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Base Information

Chemical Name:40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin
CAS No.:159351-68-5
Molecular Formula:C₅₉H₉₇NO₁₄Si
Molecular Weight:1072.5
Hs Code.:

Synonyms:40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Suppliers and Price of 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
42-O-tert-ButyldimethylsilyloxyethylRapamycin
5mg
$ 110.00

Medical Isotopes, Inc.
42-O-tert-ButyldimethylsilyloxyethylRapamycin
5 mg
$ 445.00

Total 2 raw suppliers

Chemical Property of 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Chemical Property:

Boiling Point:997.3±75.0 °C(Predicted)
Density:1.12±0.1 g/cm3(Predicted)

Purity/Quality:

> 95% ^*data from raw suppliers

42-O-tert-ButyldimethylsilyloxyethylRapamycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

There total 6 articles about 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.4%

: 53123-88-9
sirolimus

: 164162-36-1
2-(t-Butyldimethylsilyloxy)ethyl trifluoromethanesulfonate

: 159351-68-5
40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In toluene; at 60 ℃; for 4.5h; Temperature; Reagent/catalyst;

Reference yield:

: 102229-10-7
2-(tert-butyldimethylsilyloxy)ethanol

: 53123-88-9
sirolimus

: 159351-68-5
40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

Guidance literature:: 2-(tert-butyldimethylsilyloxy)ethanol; With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -40 ℃; for 0.5h;

sirolimus; With silver(I) acetate; In dichloromethane; at -40 - 40 ℃;