7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Base Information

Chemical Name:7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one
CAS No.:40017-82-1
Molecular Formula:C₁₃H₈ClN₃O₃S
Molecular Weight:321.744
Hs Code.:

7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-<i>e</i>][1,4]diazepin-2-one

Synonyms:7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Suppliers and Price of 7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

There total 10 articles about 7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 40017-87-6
1,3-Dihydro-5-o-nitrophenyl-2H-thieno<2,3-e><1,4>diazepin-2-on

: 40017-82-1
7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Guidance literature:: With sulfuryl dichloride; In acetic acid;
DOI:10.1002/ardp.19803130708

Reference yield: 20.0%

: 76053-96-8
2-Amino-N-[5-chloro-3-(2-nitro-benzoyl)-thiophen-2-yl]-acetamide

: 40017-82-1
7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Guidance literature:: With isobutyric Acid; for 0.166667h; Heating;
DOI:10.1002/ardp.19803130708

Reference yield:

: 40017-83-2
3-(2-Nitrophenyl)-3-oxopropionsaeurenitril

: 40017-82-1
7-chloro-5-(2-nitro-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one

Guidance literature:: Multi-step reaction with 6 steps

1: 48 percent / Et₃N / dimethylformamide / 4 h

2: 98 percent

3: 98 percent / NaI

4: 53 percent / NH₃

5: 53 percent / ion exchanger / dioxane; ethane-1,2-diol / 3.5 h / Heating

6: 67 percent / SO₂Cl₂ / acetic acid

With sulfuryl dichloride; ion exchanger; ammonia; triethylamine; sodium iodide; In 1,4-dioxane; ethylene glycol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19803130708