N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt

Base Information

• Chemical Name: N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt
• CAS No.: 122348-09-8
• Molecular Formula: C₄H₁₁N*C₁₅H₁₄N₂O₄S
• Molecular Weight: 391.491
• Mol file: 122348-09-8.mol

Synonyms:N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt

Chemical Property of N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt

There total 1 articles about N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-deacetyloxy-7-aminocephalosporanic acid (22252-43-3,26395-99-3,70287-30-8,72059-35-9) + salicylaldehyde (90-02-8) + tert-butylamine (75-64-9) → N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt (122348-09-8)

Guidance literature:

In water; for 3.5h;

DOI:10.1007/BF00763665

Reference yield: 80.5%

N-Salicylidene-7-amino-3-desacetoxycephalosporanic acid tert-butylamine salt (122348-09-8) → 7β-salicylideneamino-3-methyl-3-cephem-4-carboxylic acid (37850-81-0)

Guidance literature:

With salicylaldehyde; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; Ambient temperature;

DOI:10.1007/BF00763665

upstream raw materials:

3-deacetyloxy-7-aminocephalosporanic acid

salicylaldehyde

tert-butylamine

Downstream raw materials:

7β-salicylideneamino-3-methyl-3-cephem-4-carboxylic acid