Technology Process of (+/-)-2-(2-Iodoethyl)-3-methylene-1,1-dimethylcyclohexane
There total 10 articles about (+/-)-2-(2-Iodoethyl)-3-methylene-1,1-dimethylcyclohexane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(2'-Methylene-6',6'-dimethylcyclohexyl)ethanol; methanesulfonyl chloride;
With
triethylamine;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
sodium iodide;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1002/ejoc.200600361
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: copper(I) bromide / tetrahydrofuran; diethyl ether / 2 h / 0 °C
1.2: 70 percent / DMPU / tetrahydrofuran; diethyl ether / 0 - 20 °C
2.1: zinc; TiCl4 / tetrahydrofuran / 72 h / 5 °C
2.2: 61 percent / CH2Cl2; tetrahydrofuran / 5 °C
3.1: 98 percent / lithium aluminum hydride / tetrahydrofuran / 2 h / 20 °C
4.1: triethylamine / tetrahydrofuran / 1 h / 20 °C
4.2: 95 percent / sodium iodide / tetrahydrofuran / 20 °C
With
lithium aluminium tetrahydride; titanium tetrachloride; triethylamine; copper(I) bromide; zinc;
In
tetrahydrofuran; diethyl ether;
DOI:10.1002/ejoc.200600361
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: zinc; TiCl4 / tetrahydrofuran / 72 h / 5 °C
1.2: 61 percent / CH2Cl2; tetrahydrofuran / 5 °C
2.1: 98 percent / lithium aluminum hydride / tetrahydrofuran / 2 h / 20 °C
3.1: triethylamine / tetrahydrofuran / 1 h / 20 °C
3.2: 95 percent / sodium iodide / tetrahydrofuran / 20 °C
With
lithium aluminium tetrahydride; titanium tetrachloride; triethylamine; zinc;
In
tetrahydrofuran;
DOI:10.1002/ejoc.200600361
