(1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate

Base Information

• Chemical Name: (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate
• CAS No.: 702711-13-5
• Molecular Formula: C₂₄H₂₃NO₄Se
• Molecular Weight: 468.411
• Mol file: 702711-13-5.mol

Synonyms:(1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate

Chemical Property of (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate

There total 1 articles about (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzoyl isocyanate (4461-33-0) + (S)-1-Benzyloxy-3-phenylselanyl-propan-2-ol → (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate (702711-13-5)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1002/chem.200305497

Reference yield:

(1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate (702711-13-5) → C24H23NO5Se

Guidance literature:

With dipotassium hydrogenphosphate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; for 2h;

DOI:10.1002/chem.200305497

Reference yield:

(1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate (702711-13-5) → (2R)-1-amino-3-(benzyloxy)propan-2-ol (61248-83-7)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium hydrogenphosphate; m-chloroperoxybenzoic acid / tetrahydrofuran / 2 h

2: K₂CO₃ / acetone / 20 °C

3: 84 percent / aq. LiOH / tetrahydrofuran / 4 h / 20 °C

4: 94 percent / aq. NaOH / ethanol / 100 °C

With lithium hydroxide; sodium hydroxide; dipotassium hydrogenphosphate; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; ethanol; acetone;

DOI:10.1002/chem.200305497

upstream raw materials:

benzoyl isocyanate

Downstream raw materials:

(2R)-1-amino-3-(benzyloxy)propan-2-ol

(5R)-5-[(benzyloxy)methyl]-1,3-oxazolidin-2-one

(5R)-3-benzoyl-5-[(benzyloxy)methyl]-1,3-oxazolidin-2-one