5--1-iodo-3-methoxy-2-propoxybenzene

Base Information

• Chemical Name: 5--1-iodo-3-methoxy-2-propoxybenzene
• CAS No.: 127974-65-6
• Molecular Formula: C₂₃H₂₃IO₂S₂
• Molecular Weight: 522.471
• Mol file: 127974-65-6.mol

Synonyms:5--1-iodo-3-methoxy-2-propoxybenzene

Chemical Property of 5--1-iodo-3-methoxy-2-propoxybenzene

Chemical Property:

Purity/Quality:

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Technology Process of 5--1-iodo-3-methoxy-2-propoxybenzene

There total 1 articles about 5--1-iodo-3-methoxy-2-propoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-methoxy-4-n-propyloxy-5-iodobenzaldehyde (106331-89-9) + diphenyldisulfane (882-33-7) → 5--1-iodo-3-methoxy-2-propoxybenzene (127974-65-6)

Guidance literature:

With tributylphosphine; In benzene;

DOI:10.1021/jo00301a026

Reference yield:

(-)-(2R)-2-(Benzyloxy)-4-(4-fluorobenzoyl)-2,5-dihydro-furan (123195-57-3) + 5--1-iodo-3-methoxy-2-propoxybenzene (127974-65-6) → (+)-(2S,3S,4R)-2-(Benzyloxy)-4-(4-fluorobenzoyl)-3-<(3-iodo-5-methoxy-4-propoxyphenyl)bis(phenylthio)methyl>tetrahydrofuran (127974-74-7)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1) THF, -78 deg C, 2) THF, r. t.;

DOI:10.1021/jo00301a026

upstream raw materials:

3-methoxy-4-n-propyloxy-5-iodobenzaldehyde

diphenyldisulfane

Downstream raw materials:

(+)-(2S,3S,4R)-2-(Benzyloxy)-4-(4-fluorobenzoyl)-3-<(3-iodo-5-methoxy-4-propoxyphenyl)bis(phenylthio)methyl>tetrahydrofuran