7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one

Base Information

Chemical Name:7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one
CAS No.:170099-04-4
Molecular Formula:C₉H₉FN₂O
Molecular Weight:180.182
Hs Code.:
DSSTox Substance ID:DTXSID001235072
Mol file:170099-04-4.mol

Synonyms:170099-04-4;7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one;7-fluoro-6-methyl-3,4-dihydro-1H-quinoxalin-2-one;2(1H)-Quinoxalinone,7-fluoro-3,4-dihydro-6-methyl-(9CI);SCHEMBL7779719;BPJHVOVVGNUGJK-UHFFFAOYSA-N;DTXSID001235072;7-Fluoro-3,4-dihydro-6-methyl-2(1H)-quinoxalinone;7-Fluoro-3,4-dihydro-6-methylquinoxaline-2(1H)-one;7-Fluoro-6-methyl-3,4-dihydro-2(1H)-quinoxalinone;7-fluoro-6-methyl-1,2,3,4-tetrahydroquinoxalin-2-one

Suppliers and Price of 7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one

Chemical Property:

Boiling Point:345.9±42.0 °C(Predicted)
PKA:12.99±0.20(Predicted)
PSA：41.13000
Density:1.239±0.06 g/cm3(Predicted)
LogP:1.77410
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:180.06989108
Heavy Atom Count:13
Complexity:222

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1F)NC(=O)CN2

Technology Process of 7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one

There total 4 articles about 7-fluoro-6-methyl-3,4-dihydroquinoxalin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tin(II)chloride dihydrate

: N-(4-fluoro-5-methyl-2-nitrophenyl)glycine sodium salt

: 170099-04-4
7-fluoro-3,4-dihydro-6-methylquinoxaline-2(1H)-one

Guidance literature:: In ethanol;

Reference yield:

: N-(4-fluoro-5-methyl-2-nitrophenyl)glycine sodium salt

: 170099-04-4
7-fluoro-3,4-dihydro-6-methylquinoxaline-2(1H)-one

Guidance literature:: With tin(ll) chloride; In ethanol; Heating;
DOI:10.1021/jo00123a020

Reference yield:

: 452-67-5
1,4-difluoro-2-methylbenzene

: 170099-04-4
7-fluoro-3,4-dihydro-6-methylquinoxaline-2(1H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄, KNO₃

2: dimethylformamide; H₂O / 70 °C

3: SnCl₂*2H₂O / ethanol / Heating

With sulfuric acid; potassium nitrate; tin(ll) chloride; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00123a020