Technology Process of 2-(3-aminopropyl)-4-benzylmorpholine
There total 7 articles about 2-(3-aminopropyl)-4-benzylmorpholine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
ethanol;
for 1.5h;
Heating;
DOI:10.1021/jm00167a020
- Guidance literature:
-
aluminum nickel;
In
ethanol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) NaH / 1.) DMF, 0 deg C, 1 h, 2.) 140 deg C, 15 h
2: 98 percent / NaCl, H2O / dimethylformamide / 23 h / Heating
3: 87 percent / sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 5 h / Ambient temperature
4: 86 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 20 h / Ambient temperature
5: 54 percent / hydrazine monohydrate / ethanol / 1.5 h / Heating
With
water; sodium hydride; hydrazine hydrate; triphenylphosphine; sodium bis(2-methoxyethoxy)aluminium dihydride; sodium chloride; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00167a020
