(2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

Base Information

Chemical Name:(2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine
CAS No.:226215-77-6
Molecular Formula:C₂₉H₃₂N₂O₂
Molecular Weight:440.585
Hs Code.:

Synonyms:(2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

Chemical Property:

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Technology Process of (2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

There total 3 articles about (2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 492-41-1,58550-13-3,757124-50-8
(1R,2S)-norephedrine

: 226215-77-6
(2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / tetrahydrofuran / 1 h

2: 60 percent / BH₃ / tetrahydrofuran / 5 h / Heating

3: ethyl acetate / 5 h / Heating

With borane; In tetrahydrofuran; ethyl acetate;
DOI:10.1016/S0957-4166(99)00049-X

Reference yield:

: 151528-61-9
(1S,2R)-N,N'-bis-<(2-hydroxy-1-methyl-2-phenyl)ethyl>oxamide

: 226215-77-6
(2R,4S,5R,17S,19S,20R)-N,N'-ethylene(2,4,19-trimethyl-5,17,20-triphenyl)-2,17-bisoxazolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / BH₃ / tetrahydrofuran / 5 h / Heating

2: ethyl acetate / 5 h / Heating

With borane; In tetrahydrofuran; ethyl acetate;
DOI:10.1016/S0957-4166(99)00049-X