(4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Base Information

Chemical Name:(4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
CAS No.:207281-74-1
Molecular Formula:C₂₇H₃₉NO₅
Molecular Weight:457.61
Hs Code.:

Synonyms:(4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

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Technology Process of (4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

There total 1 articles about (4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108167-50-6
ethynyl, [2-isopropyl-5-methylcyclohexyl(1R,2S,5R)]ether

: 107202-54-0
(S)-((S)-3-methyl-1-phthalimidobutyl)oxirane

: 207281-74-1
(4R,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-7-methyl-octanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: (5R)-5-((1S)-3-methyl-1-phthalimidobutyl)dihydrofuran-2(3H)-one

Guidance literature:: With n-butyllithium; boron trifluoride diethyl etherate; water; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, hexane, -78 deg C, 1.5 h, 2.) -78 deg C to room temperature;
DOI:10.1021/jo9720851