quinolinyl)ethenyl]phenyl]-2-propenyl]-,-dimethyl-

Base Information

• Chemical Name: quinolinyl)ethenyl]phenyl]-2-propenyl]-,-dimethyl-
• CAS No.: 168214-68-4
• Molecular Formula: C₂₉H₂₆ClNO
• Molecular Weight: 439.985
• Mol file: 168214-68-4.mol

Synonyms:Benzenemethanol,2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-propenyl]-a,a-dimethyl- (9CI)

Chemical Property of quinolinyl)ethenyl]phenyl]-2-propenyl]-,-dimethyl-

Chemical Property:

• PSA: 33.12000
• LogP: 7.54190

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of quinolinyl)ethenyl]phenyl]-2-propenyl]-,-dimethyl-

There total 2 articles about quinolinyl)ethenyl]phenyl]-2-propenyl]-,-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol (807638-71-7) + 1-(sulfanylmethyl)cyclopropaneacetic acid (162515-68-6) → C29H26ClNO (168214-67-3) + 2-[2-((E)-3-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-allyl)-phenyl]-propan-2-ol (168214-68-4) + Montelukast sodium (151767-02-1)

Guidance literature:

With sodium t-butanolate; In tetrahydrofuran; toluene; at -10 - 20 ℃; Inert atmosphere; Large scale reaction;

DOI:10.1021/op900311z

Reference yield:

2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol (807638-71-7) → 2-[2-((E)-3-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-allyl)-phenyl]-propan-2-ol (168214-68-4) + 7-Chloro-2-{(E)-2-[3-(1,1-dimethyl-1,3,4,5-tetrahydro-benzo[c]oxepin-3-yl)-phenyl]-vinyl}-quinoline

Guidance literature:

With chromatography under protic conditions; at 10 ℃; Rate constant; Kinetics; chromatographic separation;

DOI:10.1021/ac00109a059

upstream raw materials:

2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol

1-(sulfanylmethyl)cyclopropaneacetic acid