ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

Base Information

Chemical Name:ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate
CAS No.:1167439-03-3
Molecular Formula:C₂₁H₁₈FIN₄O₂
Molecular Weight:504.302
Hs Code.:

Synonyms:ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

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Chemical Property of ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

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Technology Process of ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

There total 1 articles about ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 766-98-3
1-ethynyl-4-fluorobenzene

: 1167438-95-0
C₁₃H₁₄N₄O₂

: 1167439-03-3
ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

Guidance literature:: With copper(l) iodide; Iodine monochloride; triethylamine; In tetrahydrofuran; dichloromethane; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1039/b818909a

Reference yield: 35.0%

: 1167439-03-3
ethyl 2-(4-(4-fluorophenyl)-5-iodo-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoate

: 1692-15-5
4-pyridylboronic acid

: 1167439-11-3
2-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-3-(1H-indol-3-yl)propanoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 150 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;
DOI:10.1039/b818909a