(S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

Base Information

• Chemical Name: (S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide
• CAS No.: 167010-30-2
• Molecular Formula: C12H12 F2 N2 O3
• Molecular Weight: 270.236
• Hs Code.: 2934999090
• Mol file: 167010-30-2.mol

Synonyms:Acetamide,N-[[3-(3,5-difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]-, (S)-; (S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

Chemical Property of (S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

Chemical Property:

• Vapor Pressure: 1.58E-08mmHg at 25°C
• Refractive Index: 1.523
• Boiling Point: 456.7°Cat760mmHg
• Flash Point: 230°C
• PSA: 62.13000
• Density: 1.351g/cm³
• LogP: 2.33140
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(S)-N-((3-(3,5-Difluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

There total 2 articles about (S)-N-[[3-(3,5-Difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-[N-3-(3,5-difluorophenyl)-2-oxo-5-oxazolidinyl]methyl amine (883230-99-7) + acetic anhydride (108-24-7) → N-((5S)-3-(3,5-Difluorophenyl)-2-oxooxazolidin-5-ylmethyl)acetamide (167010-30-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield:

→ N-((5S)-3-(3,5-Difluorophenyl)-2-oxooxazolidin-5-ylmethyl)acetamide (167010-30-2)

Guidance literature:

Reference yield:

N-((5S)-3-(3,5-Difluorophenyl)-2-oxooxazolidin-5-ylmethyl)acetamide (167010-30-2) → (S)-N-[[3-(4-iodo-3,5-difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide (167010-31-3)

Guidance literature:

With iodine; silver trifluoroacetate; In chloroform; acetonitrile; at 20 ℃;

upstream raw materials:

(S)-[N-3-(3,5-difluorophenyl)-2-oxo-5-oxazolidinyl]methyl amine

acetic anhydride

Downstream raw materials:

(S)-N-[[3-(4-iodo-3,5-difluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide