1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene

Base Information

• Chemical Name: 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene
• CAS No.: 116425-56-0
• Molecular Formula: C₁₅H₂₂
• Molecular Weight: 202.34
• Mol file: 116425-56-0.mol

Synonyms:1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene

Chemical Property of 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene

There total 2 articles about 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-methyl-1-(1-methyl-2-methylenecyclopentyl)-2-cyclohexen-4-one (116425-55-9) + Methylenetriphenylphosphorane (19493-09-5) → 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene (116425-56-0)

Guidance literature:

In diethyl ether; tert-butyl alcohol; for 4h;

DOI:10.1039/c39870001445

Reference yield:

Methyltriphenylphosphonium bromide (1779-49-3) + 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-2-cyclohexen-4-one (116425-55-9) → 1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene (116425-56-0)

Guidance literature:

With potassium tert-butylate; Yield given. Multistep reaction; 1.) Et₂O, ^tBuOH, reflux, 1 h, 2.) ether, 55 deg C, 2 h;

DOI:10.1021/jo00280a039

Reference yield: 73.0%

1-methyl-1-(1-methyl-2-methylenecyclopentyl)-4-methylene-2-cyclohexene (116425-56-0) → (+/-)-trichodiene (61505-17-7) + (R)-3,6-Dimethyl-3-((R)-1-methyl-2-methylene-cyclopentyl)-cyclohexene (116425-57-1)

Guidance literature:

With ammonia; sodium; In tetrahydrofuran; at -78 ℃; for 0.75h; Yields of byproduct given;

DOI:10.1021/jo00280a039

upstream raw materials:

Methyltriphenylphosphonium bromide

1-methyl-1-(1-methyl-2-methylenecyclopentyl)-2-cyclohexen-4-one

Methylenetriphenylphosphorane

Downstream raw materials:

(+/-)-trichodiene

(R)-3,6-Dimethyl-3-((R)-1-methyl-2-methylene-cyclopentyl)-cyclohexene