5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene

Base Information

• Chemical Name: 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene
• CAS No.: 960319-17-9
• Molecular Formula: C₆₂H₆₆N₈O₁₂S₄
• Molecular Weight: 1243.52
• Mol file: 960319-17-9.mol

Synonyms:5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene

Chemical Property of 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene

There total 3 articles about 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

4-nitrobenzaldehyde hydrazone (6310-10-7) + 5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrakis[(chlorocarbonyl)methoxy]-thiacalix[4]arene (700371-96-6,700813-30-5) → 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene (960319-17-9)

Guidance literature:

With pyridine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1070/MC2006v016n06ABEH002404

Reference yield: 26.0%

5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrakis-[(hydrazidocarbonyl)methoxy]-2,8,14,20-tetrathiacalix[4]arene + 4-nitrobenzaldehdye (555-16-8) → 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene (960319-17-9)

Guidance literature:

In chloroform; at 20 ℃; for 20h;

DOI:10.1070/MC2006v016n06ABEH002404

Reference yield:

5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrakis[(ethoxycarbonyl)methoxy]-2,8,14,20-tetrathiacalix[4]arene (210706-03-9,210780-04-4,210780-05-5,210780-06-6,252287-26-6) → 5,11,17,23-tetra-tert-butyl-25,27-bis[(4-nitrobenzylidene)-hydrazinocarbonylmethyloxy]-26,28-[N,N'-hydrazinylene-bis(carbonylmethyleneoxy)]-2,8,14,20-tetrathiacalix[4]arene (960319-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / Reflux

2: chloroform / 20 h / 20 °C

With hydrazine hydrate; In ethanol; chloroform;

DOI:10.1070/MC2006v016n06ABEH002404

upstream raw materials:

5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrakis[(ethoxycarbonyl)methoxy]-2,8,14,20-tetrathiacalix[4]arene

4-nitrobenzaldehdye

4-nitrobenzaldehyde hydrazone

5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrakis[(chlorocarbonyl)methoxy]-thiacalix[4]arene