(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

Base Information

Chemical Name:(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid
CAS No.:1425927-07-6
Molecular Formula:C₁₈H₁₆N₂O₆S
Molecular Weight:388.401
Hs Code.:

Synonyms:(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

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Chemical Property of (2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

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Technology Process of (2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

There total 8 articles about (2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 1425927-05-4
methyl (2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetate

: 1425927-07-6
(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

Guidance literature:: methyl (2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetate; With water; potassium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

With hydrogenchloride; In water; ethyl acetate;

Reference yield:

: 2721-59-7
3-methylcarbostyril

: 1425927-07-6
(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid; nitric acid / 2 h / Cooling with ice

2: hydrogen; palladium 10% on activated carbon; acetic acid / 3 h / 2585.81 Torr

3: pyridine / 96 h / 20 °C

4: water; potassium hydroxide / tetrahydrofuran; methanol / 2 h / 20 °C

With pyridine; sulfuric acid; palladium 10% on activated carbon; water; hydrogen; nitric acid; acetic acid; potassium hydroxide; In tetrahydrofuran; methanol;

Reference yield:

: 1425927-69-0
3-methyl-6-nitro-1H-quinolin-2-one

: 1425927-07-6
(2-{[(3-methyl-2-oxo-1,2-dihydroquinolin-6-yl)amino]sulfonyl}phenoxy)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen; palladium 10% on activated carbon; acetic acid / 3 h / 2585.81 Torr

2: pyridine / 96 h / 20 °C

3: water; potassium hydroxide / tetrahydrofuran; methanol / 2 h / 20 °C

With pyridine; palladium 10% on activated carbon; water; hydrogen; acetic acid; potassium hydroxide; In tetrahydrofuran; methanol;