3-methylquinolin-2(1H)-one

Base Information

Chemical Name:3-methylquinolin-2(1H)-one
CAS No.:2721-59-7
Molecular Formula:C10H9 N O
Molecular Weight:159.188
Hs Code.:2933790090
DSSTox Substance ID:DTXSID90949939
Nikkaji Number:J112.924D
Wikidata:Q27461644
Metabolomics Workbench ID:53742
ChEMBL ID:CHEMBL3586688
Mol file:2721-59-7.mol

Synonyms:2721-59-7;3-methylquinolin-2(1H)-one;3-methyl-1,2-dihydroquinolin-2-one;3-METHYLQUINOLIN-2-ONE;3-Methylcarbostyril;2-Hydroxy-3-methylquinoline;3-methyl-1H-quinolin-2-one;3-methylquinolin-2-ol;3-Methyl-2-quinolinone;2(1H)-Quinolinone, 3-methyl-;3-Methyl-2-oxo-1,2-dihydroquinoline;3-methyl-2-quinolone;Carbostyril, 3-methyl-;3-Methyl-quinolin-2-ol;3-Methylhydroquinolin-2-one;CHEMBL3586688;methylquinolone;methylhydroxyquinoline;SCHEMBL248620;3-Methyl-2(1H)-quinolinone;CHEBI:1588;CHEBI:20114;3-Methyl-2(1H)-quinolinone #;DTXSID90949939;AMY33224;CAA72159;BDBM50096297;STL572712;ZB0690;AKOS006289779;AKOS017405187;SB68177;AS-37316;FT-0760991;C06345;EN300-173928;A876999;Q27461644;Z1198181962;J5I

Suppliers and Price of 3-methylquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-methyl-1,2-dihydroquinolin-2-one
10mg
$ 155.00

Matrix Scientific
3-Methylquinolin-2-one 97%
1g
$ 791.00

Crysdot
3-Methylquinolin-2(1H)-one 95+%
250mg
$ 297.00

Crysdot
3-Methylquinolin-2(1H)-one 95+%
1g
$ 744.00

Chemenu
3-Methylquinolin-2-one 95%
1g
$ 702.00

Atlantic Research Chemicals
3-Methylquinolin-2-one 95%
1gm:
$ 328.71

American Custom Chemicals Corporation
3-METHYLQUINOLIN-2-ONE 95.00%
5MG
$ 495.79

Alichem
2-Hydroxy-3-methylquinoline
1g
$ 377.13

Alichem
2-Hydroxy-3-methylquinoline
5g
$ 1198.33

AK Scientific
3-Methylquinolin-2(1H)-one
1g
$ 1117.00

Total 10 raw suppliers

Chemical Property of 3-methylquinolin-2(1H)-one

Chemical Property:

Vapor Pressure:5.94E-05mmHg at 25°C
Melting Point:234-235 °C
Refractive Index:1.573
Boiling Point:346°Cat760mmHg
PKA:11.84±0.70(Predicted)
Flash Point:201.8°C
PSA：32.86000
Density:1.136g/cm³
LogP:1.83650
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:159.068413911
Heavy Atom Count:12
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

3-methyl-1,2-dihydroquinolin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CC=CC=C2NC1=O

Technology Process of 3-methylquinolin-2(1H)-one

There total 53 articles about 3-methylquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1035669-84-1
C₁₂H₁₃NO

: 2721-59-7
3-methylcarbostyril

Guidance literature:: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 40 ℃;
DOI:10.1016/j.tetlet.2008.03.144

Reference yield: 97.0%

: 80818-45-7
N-phenyl methyl-2 phenyl-3 propene-2 amide

: 2721-59-7
3-methylcarbostyril

Guidance literature:: With aluminum (III) chloride; In chlorobenzene; at 0 - 120 ℃; for 1h;
DOI:10.1021/acs.jmedchem.5b00772

Reference yield: 91.0%

: 1071176-99-2
N-acetyl-N-[2-(bromomethyl)phenyl]acrylamide

: 2721-59-7
3-methylcarbostyril

Guidance literature:: N-acetyl-N-[2-(bromomethyl)phenyl]acrylamide; With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triethylamine; In acetonitrile; for 5h; Reflux; Inert atmosphere;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; for 3h; Reflux; Inert atmosphere;
DOI:10.1055/s-2008-1077875