Technology Process of C21H21FN6O4
There total 13 articles about C21H21FN6O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate;
In
water; N,N-dimethyl-formamide;
at 90 ℃;
for 5h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium carbonate / water; 1,4-dioxane / 15 h / 0 - 20 °C
2: acetic acid; sodium nitrite; zinc / water / 1.5 h / 0 - 20 °C
3: hydrogenchloride / dichloromethane; 1,4-dioxane / 15 h / 0 °C / Inert atmosphere
4: acetic acid / 5 h
5: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 5 h / 90 °C / Inert atmosphere
With
hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; acetic acid; zinc; sodium nitrite;
In
1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / dichloromethane; 1,4-dioxane / 15 h / 0 °C / Inert atmosphere
2: acetic acid / 5 h
3: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 5 h / 90 °C / Inert atmosphere
With
hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; acetic acid;
In
1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;